منابع مشابه
Aspirin in the chemoprevention of colorectal neoplasia: an overview.
Considerable evidence supports the effectiveness of aspirin for chemoprevention of colorectal cancer (CRC) in addition to its well-established benefits in the prevention of vascular disease. Epidemiologic studies have consistently observed an inverse association between aspirin use and risk of CRC. A recent pooled analysis of a long-term posttrial follow-up of nearly 14,000 patients from four r...
متن کاملChemoprevention of colorectal cancer in individuals with previous colorectal neoplasia: systematic review and network meta-analysis
OBJECTIVE To assess the comparative efficacy and safety of candidate agents (low and high dose aspirin, non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs), calcium, vitamin D, folic acid, alone or in combination) for prevention of advanced metachronous neoplasia (that is, occurring at different times after resection of initial neoplasia) in individuals with previous colorectal neoplasi...
متن کاملCancer Prevention Research Chemoprevention of Colorectal Neoplasia by Estrogen: Potential Role of Vitamin D Activity
Postmenopausal hormone replacement therapy lowers colon cancer incidence. In humans, the mechanism is unknown, but animal models suggest that it may involve activation of the vitamin D receptor (VDR) pathway. The aims of our study were to determine whether estrogen intervention affects global gene expression in rectal mucosal biopsies and whether vitamin D–related genes are
متن کاملChemoprevention of colorectal neoplasia by estrogen: potential role of vitamin D activity.
Postmenopausal hormone replacement therapy lowers colon cancer incidence. In humans, the mechanism is unknown, but animal models suggest that it may involve activation of the vitamin D receptor (VDR) pathway. The aims of our study were to determine whether estrogen intervention affects global gene expression in rectal mucosal biopsies and whether vitamin D-related genes are affected. Estradiol ...
متن کاملAnti-inflammatory Approaches for Colorectal Cancer Chemoprevention
1 2 Alexandra M. Fajardo and Gary A. Piazza 3 Drug Discovery Research Center Mitchell Cancer Institute 4 University of South Alabama 5 1660 Springhill Ave. Suite 3029 6 Mobile AL 36604, USA 7 Email: [email protected], [email protected] 8 9
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ژورنال
عنوان ژورنال: Clinics in Colon and Rectal Surgery
سال: 2008
ISSN: 1531-0043,1530-9681
DOI: 10.1055/s-0028-1089947